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Precautions and Warnings With the Oxybutynin Patch

Specific Warnings and Precautions for the Oxybutynin Patch

Warnings and precautions to be aware of prior to using the oxybutynin patch include the following:
  • In rare cases, this medication can cause life-threatening swelling of the face, lips, tongue, or throat. This can occur quickly, even after the first dose. Seek immediate medical attention if such swelling occurs.


  • The oxybutynin patch can slow the digestive system. This can cause problems, especially for people who already have a slow digestive system due to other medical problems.
  • This medication may make glaucoma worse. If you have glaucoma and use the oxybutynin patch, your healthcare provider may need to monitor you more closely.
  • The kidneys and liver help to remove oxybutynin from your body. If you have kidney or liver disease, you may require extra monitoring by your healthcare provider and may need to take a lower oxybutynin patch dosage.
  • The oxybutynin patch can cause blurred vision, dizziness, and drowsiness. Be sure to see how the oxybutynin patch affects you before driving or operating heavy machinery.
  • The oxybutynin patch can decrease your ability to sweat, which may increase your risk of heat stroke. Be sure to stay well hydrated in the heat.
  • The oxybutynin patch may potentially interact with a number of other medications (see Drug Interactions With the Oxybutynin Patch).
  • The oxybutynin patch is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known (see Oxytrol and Pregnancy).
  • It is not known whether oxybutynin passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the patch (see Oxytrol and Breastfeeding).

Drug Information - Oxybutynin Patch

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