Warnings and Precautions With Ondansetron

Before taking ondansetron, be sure to talk to your healthcare provider about any warnings and precautions with ondansetron, such as drug interactions and allergic reactions. You should also tell your healthcare provider about any medications you are currently taking and any health conditions you may have, including liver problems, arrhythmia, or phenylketonuria.

Ondansetron Hydrochloride

Ondansetron: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking ondansetron hydrochloride (Zofran^®) if you have:

Liver problems, including cirrhosis
An arrhythmia (an irregular heart rhythm), especially long QT syndrome
Phenylketonuria
Any allergies, including allergies to foods, dyes, or preservatives.

Also, let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant (see Zofran During Pregnancy)
Are breastfeeding
Have severe or constant nausea or vomiting that is not helped by ondansetron. Also, talk with your healthcare provider if you are vomiting blood.
Have severe vomiting and diarrhea. This combination of problems can lead to dehydration and electrolyte imbalances.

It's important to also tell your healthcare provider about all of the medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Warnings and Precautions With Ondansetron Continued: Page 2)