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Drug Interactions With Omeprazole
Potential drug interactions with omeprazole may involve medications such as Celexa, Valium, and iron supplements. For people taking omeprazole, drug interactions can alter the amounts of the medications in your blood, potentially increasing your risk of side effects or decreasing the effectiveness of the medications.
Omeprazole (Prilosec®) can potentially interact with other medications. Some of these medicines that may lead to omeprazole drug interactions include:
- Ampicillin (Principen®)
- Cilostazol (Pletal®)
- Citalopram (Celexa®)
- Clopidogrel (Plavix®)
- Diazepam (Valium®)
- Digoxin (Digitek®, Lanoxin®)
- Disulfiram (Antabuse®)
- Certain diuretics, such as:
- Bumetanide (Bumex®)
- Chlorothiazide (Diuril®)
- Chlorthalidone (Thalitone®)
- Ethacrynic acid (Edecrin®)
- Furosemide (Lasix®)
- Hydrochlorothiazide (Esidrix®, HydroDIURIL®, Microzide®, Oretic®)
- Metolazone (Zaroxolyn®)
- Torsemide (Demadex®)
- Erlotinib (Tarceva®)
- Escitalopram (Lexapro®)
- HIV medications
- Iron supplements
- Ketoconazole (Nizoral®)
- Methotrexate (Rheumatrex®, Trexall®)
- Phenytoin (Dilantin®, Phenytek®)
- Rifampin (Rifadin®)
- St. John's wort
- Tacrolimus (Prograf®)
-
Voriconazole (Vfend®)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD