Drug Interactions With Omeprazole

Potential drug interactions with omeprazole may involve medications such as Celexa, Valium, and iron supplements. For people taking omeprazole, drug interactions can alter the amounts of the medications in your blood, potentially increasing your risk of side effects or decreasing the effectiveness of the medications.

 

An Overview of Drug Interactions With Omeprazole

Omeprazole (Prilosec®) can potentially interact with other medications. Some of these medicines that may lead to omeprazole drug interactions include:
 

 

Omeprazole Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when omeprazole is combined with any of the drugs listed above.
 
Ampicillin (Principen)
Omeprazole can decrease the absorption of ampicillin into your bloodstream, perhaps making it less effective. Your healthcare provider may need to increase your ampicillin dose.
 
Atazanavir (Reyataz)
Omeprazole can decrease the level of atazanavir in your blood, perhaps making it less effective. Your healthcare provider may need to increase your atazanavir dose.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;