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Omeprazole/Sodium Bicarbonate Dosage

Omeprazole/Sodium Bicarbonate Dosage for Duodenal Ulcers
The recommended dose for treating duodenal ulcers is omeprazole/sodium bicarbonate 20 mg once daily for four weeks.
Omeprazole/Sodium Bicarbonate Dosage for Gastric Ulcers
The recommended dose for stomach ulcers (gastric ulcers) is omeprazole/sodium bicarbonate 40 mg once daily for four to eight weeks.
Omeprazole/Sodium Bicarbonate Dosage for GERD and Erosive Esophagitis
The recommended dose for gastroesophageal reflux disease (GERD) is omeprazole/sodium bicarbonate 20 mg once daily for up to four weeks. For people with GERD and erosive esophagitis, the recommended dose is 20 mg for four to eight weeks. The medication can be continued if needed to prevent erosive esophagitis from returning.
Omeprazole/Sodium Bicarbonate Dosage for Stress Ulcer Prophylaxis
The recommended dosage for preventing upper gastrointestinal bleeding (from ulcers) in critically ill people (such as people in the intensive care unit) is 40 mg initially, followed by 40 mg in six to eight hours. After this initial dosing, 40 mg is taken once daily for 14 days. Only the 40 mg powder for oral suspension packets (not the capsule form) is approved for this use.
Nonprescription Omeprazole/Sodium Bicarbonate Dosage for Heartburn
The recommended nonprescription omeprazole/sodium bicarbonate (Zegerid OTC™) dose for treating frequent heartburn is one 20-mg capsule once daily in the morning, at least one hour before eating.
Nonprescription omeprazole/sodium bicarbonate is approved for a 14-day course of treatment, with repeated courses allowed once every four months. However, many (if not most) people who take medications like this one need to take them on a long-term basis. There is no reason that nonprescription omeprazole/sodium bicarbonate cannot be used on a long-term basis, except that an evaluation by a healthcare provider is probably warranted, to rule out the possibility of more serious problems.
If your healthcare provider recommends that you take nonprescription omeprazole/sodium bicarbonate for longer than 14 days, you may completely disregard the label directions that warn against doing so.
The prescription version of omeprazole/sodium bicarbonate can be taken during the day or at bedtime, as long as it is taken on an empty stomach at least one hour before a meal. This suggests that you could probably also take the nonprescription version of the medication at bedtime if you desire (instead of in the morning), as long as you take it on an empty stomach.

Omeprazole/Sodium Bicarbonate Drug Information

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