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Precautions and Warnings With Nitroglycerin Tablets

Nitroglycerin tablets aren't right for everyone, so if you have problems with dehydration, anemia, or low blood pressure, tell your healthcare provider. Other precautions for nitroglycerin tablets include warnings of potential problems this drug may cause, such as dangerously low blood pressure, headaches, and allergic reactions. Also, you may not be able to use this medicine if you are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Using Nitroglycerin Tablets?

You should talk with your healthcare provider prior to using a nitroglycerin tablet (Nitrostat®) if you have:
  • Low blood pressure (hypotension)
  • Dehydration
  • Anemia
  • Increased intracranial pressure (high pressure within the skull)
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Nitroglycerin Tablet Precautions and Warnings

Some warnings and precautions to be aware of prior to using this angina medication include the following:
  • If you have used 3 nitroglycerin tablets within 15 minutes and you still have chest pain, it is time to seek immediate medical attention. You may be having a heart attack.
  • Do not use nitroglycerin tablets more frequently or at a higher dose than absolutely necessary. Using them too often can result in a tolerance to the drug, which means your body becomes accustomed to it and no longer responds to the medication.
  • Nitroglycerin tablets can sometimes cause dangerously low blood pressure (hypotension). Alcohol or certain other medications can make this worse (see Drug Interactions With Nitroglycerin Tablets for more information). People who already have low blood pressure or who are dehydrated are particularly at risk for this complication.
  • Nitroglycerin tablets often causes headaches. If the headaches become intolerable, talk with your healthcare provider.
  • This medication does not work for all types of chest pain (angina). If your chest pain gets worse when you use a nitroglycerin tablet, let your healthcare provider know right away.
  • Some people may be allergic to nitroglycerin tablets. Let your healthcare provider know if you develop any signs of an allergic reaction, such as:
    • Hives
    • Itching
    • Unexplained swelling
    • Difficulty breathing.
  • This product is a pregnancy Category C medication, which means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Nitrostat and Pregnancy for more information).
  • It is unknown if this drug passes through breast milk. Therefore, if you are breastfeeding or plan to start, check with your healthcare provider or your child's healthcare provider before using this medicine (see Nitrostat and Breastfeeding).
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Nitroglycerin Tablet Information

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