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What Is Nitroglycerin Anal Ointment Used For?

Although most anal fissures heal up on their own within a few weeks, treatment may be necessary in some cases. Nitroglycerin anal ointment is used twice a day to help reduce moderate-to-severe pain caused by chronic anal fissures. It is currently approved for use in adults only. If your child has an anal fissure, other treatment options, such as dietary changes, may be recommended first.

An Overview of Uses for Nitroglycerin Anal Ointment

Nitroglycerin anal ointment (Rectiv™) is a prescription medication approved for the treatment of moderate-to-severe pain caused by chronic anal fissures.
An anal fissure is a tear in the lining of the anus. Often the result of constipation (since passing large or hard stools can cause the tears), anal fissures are a common problem. They typically cause pain and bleeding. In fact, anal fissures can be quite painful.
Most fissures heal up on their own rather quickly (within a few weeks), especially once the constipation is treated. Sometimes, though, anal fissures may not heal quickly and can be a chronic problem. In such cases, treatment may be necessary.
Topical ointments, such as nitroglycerin anal ointment or nifedipine ointment, are usually tried first. Sometimes surgery may be necessary in severe cases. Nitroglycerin anal ointment can help treat the sometimes overwhelming pain caused by anal fissures.

How Does It Work?

Nitroglycerin anal ointment works to treat anal fissures by causing the muscle in the anus to relax, and also by dilating the blood vessels in the area, causing improved blood flow.

Is Nitroglycerin Anal Ointment Used in Children?

Nitroglycerin anal ointment is not approved for use in children. If your healthcare provider recommends this product for your child, be sure to discuss both the risks and benefits.
Anal fissures are common in infants and children, and are usually due to constipation. In most cases, adjusting the child's diet can adequately treat the constipation, allowing the fissures to heal and preventing future ones. If dietary changes are not possible or are not effective, talk with your child's healthcare provider about whether a laxative or stool softeners might be appropriate.
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Nitroglycerin Anal Ointment Information

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