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Nitroglycerin Anal Ointment Dosage

The standard nitroglycerin anal ointment dosage is to apply it twice daily for up to three weeks. To use this medication, start by covering the finger with a glove, finger cot, or even plastic wrap. Then, apply one inch of the medication to the finger and gently insert it into the anus. Do not insert it further than the first finger joint.

An Introduction to Dosing With Nitroglycerin Anal Ointment

There is only one standard dosage of nitroglycerin anal ointment (Rectiv™). As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Standard Nitroglycerin Anal Ointment Dosage

The standard starting dose of nitroglycerin anal ointment for treating pain due to anal fissures in adults is approximately one inch of ointment (375 mg, containing 1.5 mg of nitroglycerin) applied every 12 hours, for up to 3 weeks.
Usually, one inch of the ointment is first applied to the finger (which has been covered with a glove, finger cot, or plastic wrap). The ointment is then gently applied inside the anus by inserting the finger no further than the first finger joint. If this is too painful, simply start by applying it to the outside of the anus.

General Information on Using Nitroglycerin Anal Ointment

Some considerations to keep in mind during treatment with nitroglycerin anal ointment include the following:
  • With nitroglycerin products used for treating chest pain, it is very important that the body gets a 10- to 12-hour break from the drug every day. Without this break, your body will become accustomed to the nitroglycerin very quickly, and it will completely stop working for you within 24 hours. However, this does not apply to nitroglycerin anal ointment for treating anal fissures. No daily break is needed.
  • If you apply the ointment with your bare, uncovered finger (which is not recommended), be sure to thoroughly wash your hands beforehand. It is best to use a glove, finger cot, or even plastic wrap.
  • For the medication to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your dosage or nitroglycerin anal ointment dosing in general, please talk with your doctor, nurse, or pharmacist.
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Nitroglycerin Anal Ointment Information

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