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Nicotine Nasal Spray

How Does Nicotine Nasal Spray Work?

Nicotine nasal spray is a nicotine replacement medication that is sprayed into the nose. The nicotine is absorbed from the nose into the body, where it helps replace some of the nicotine your body was used to getting from cigarettes. This reduces nicotine withdrawal symptoms, such as cravings, that occur when you stop smoking.
 

Clinical Effects of Nicotine Nasal Spray

In clinical studies, nicotine nasal spray was shown to help people quit smoking more than a placebo. In these studies, up to 58 percent of people using nicotine nasal spray were able to quit smoking for at least four weeks, compared to 32 percent of people given a placebo (a medication with no active ingredients). One year later, up to 27 percent of those who had used nicotine nasal spray were still not smoking, compared to up to 15 percent of people who had been given the placebo.
 
In addition, people given nicotine nasal spray experienced more relief from nicotine withdrawal symptoms than those given the placebo. The nicotine nasal spray group also had a reduced urge to smoke.
 

When and How to Use It

Some general considerations to keep in mind during treatment with nicotine nasal spray include the following:
 
  • This medication comes as a nasal spray. It is usually sprayed once or twice in each nostril every hour.
     
  • Do not use the nasal spray more than 5 times in one hour or 40 times in a day.
     
  • Nicotine nasal spray should be used as a part of a complete quit-smoking program that includes support groups, counseling, or behavioral change strategies.
     
  • You should avoid smoking, chewing tobacco, using snuff, or using any other nicotine products while you use this medication. Using more than one nicotine product increases your nicotine blood levels, increasing your risk for side effects.
     
  • The nasal spray should be "primed" before the first use, and again if it is not used for 24 hours. To prime the medication, pump the bottle into a tissue until you see a fine spray. This usually takes six to eight pumps.
     
  • To use nicotine nasal spray, first blow your nose if it is not already clear. Then tilt your head back slightly, insert the tip of the bottle into your nose, and spray one time. Avoid sniffing, swallowing, or inhaling while spraying the medication, since the medication is absorbed through the lining of the nose. Repeat into the other nostril.
     
  • Nicotine nasal spray comes with an information sheet explaining the proper way to use it. Read this sheet carefully before using this medication and each time you get your prescription filled. Ask your healthcare provider or pharmacist if you have any questions about how to use this product.
     
  • For the medication to work properly, it must be used as prescribed.
     
7 Reasons to Stop Smoking

Nicotine Nasal Spray Drug Information

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