Side Effects of Niacin Extended-Release/Simvastatin

Common side effects that have been reported with niacin extended-release/simvastatin include flushing, headache, and itching. While most side effects are mild and do not require medical attention, you should contact your healthcare provider immediately if you experience unexplained muscle pain, tenderness, or weakness (especially if accompanied by a fever). In clinical studies, up to 14 percent of people who developed niacin extended-release/simvastatin side effects stopped taking the medication.

An Introduction to Niacin Extended-Release/Simvastatin Side Effects

As with any medicine, side effects are possible with niacin extended-release/simvastatin (Simcor®). However, not everyone who takes the drug will have problems. In fact, most people tolerate the medicine well. If side effects do occur, in most cases, they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
 
In clinical studies, up to 14 percent of people taking niacin extended-release/simvastatin stopped their medicine because of side effects. Most people who stopped the medication did so because of flushing, a sudden reddening and warmth of the face, neck, and/or upper chest.
 
When taking this medicine, if you experience unexplained muscle pain, tenderness, or weakness (especially if accompanied by a fever or feeling of illness), it is important to contact your healthcare provider immediately.
 
(This article covers many, but not all, of the possible side effects with niacin extended-release/simvastatin. Your healthcare provider can discuss a more complete list of side effects with you.)
 
(Side Effects of Niacin Extended-Release/Simvastatin Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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