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Side Effects of Niacin Extended-Release/Simvastatin

Common Side Effects

Niacin extended-release/simvastatin has been studied in clinical trials, with hundreds of people having been evaluated. In these studies, side effects were documented and compared to problems that occurred in a similar group of people taking just simvastatin (without the extended-release niacin).
Based on these studies, the most common niacin extended-release/simvastatin side effects included:
  • Flushing -- in up to 59 percent of people
  • Headache -- up to 4.5 percent
  • Itching -- up to 3.2 percent
  • Nausea -- up to 3.2 percent
  • Back pain -- up to 3.2 percent
  • Diarrhea -- up to 3 percent.

Final Thoughts

You may experience some or none of the side effects listed in this article. There is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
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Niacin Extended-Release/Simvastatin Information

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