Serious Side Effects Seen With Niacin Extended-Release/Simvastatin
There are several side effects that you should report immediately to your healthcare provider. These include, but are not limited to:
- Muscle pain, tenderness, or weakness, especially if you also have a fever or feel ill, since these may be signs of serious breakdown of muscle, known as rhabdomyolysis (see Simcor and Muscle Pain)
- Significant, unexplained changes in the amount of urine you produce (which may be a sign of kidney problems)
- Signs of liver damage (see Simcor and Liver Problems), such as:
- Yellowing of the whites of the eyes or skin (jaundice)
- Upper-right abdominal pain (stomach pain)
- Dark urine
- High liver enzymes (found using a blood test)
- Signs of a stomach ulcer, such as:
- Severe heartburn
- Stomach pain
- Loss of appetite
- Dizziness
- Vomiting blood
- Blood in the stool (seen as dark-colored stools)
- Easy bruising or bleeding (or bleeding that is slow to stop)
- Gout
- High blood sugar (hyperglycemia)
- Signs of low blood pressure (hypotension), such as lightheadedness, dizziness, or fainting
- An irregular heart rhythm (arrhythmia)
- Signs of an allergic reaction, such as:
- A rash
- Itching
- Joint pain
- Anemia
- Low white blood cell counts
- Sensitivity to the sun
- Fever and chills
- Flushing
- A general ill feeling
- Hives
- Wheezing or difficulty breathing
- Swelling of the mouth, tongue, or throat.