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Niacin Extended-Release/Simvastatin

When and How Should I Take Niacin Extended-Release/Simvastatin?

Some general considerations for when and how to take the medication include:
  • Your niacin extended-release/simvastatin medication should be taken at bedtime with a low-fat snack.
  • Alcohol and hot drinks may worsen flushing symptoms and itchy skin, which are common side effects of the drug. Alcohol and hot drinks should be avoided close to the time that the medicine is taken.
  • Swallow the tablet whole with a glass of water. Do not break, chew, or crush the tablets.
  • For niacin extended-release/simvastatin to work properly, you have to take it as prescribed. It will not work if you stop taking it.

Dietary Instructions

It is recommended that people who are on niacin extended-release/simvastatin avoid drinking large quantities of grapefruit juice because it can increase the levels of simvastatin (one of the active ingredients) in the blood. This could increase the risk of developing serious muscle problems. If you want to continue drinking grapefruit juice, talk to your doctor about other cholesterol-lowering medications that you can take.
(Click Simcor and Grapefruit for more information.)
As with any cholesterol medication, you should continue to eat a low fat, low cholesterol diet as part of your cholesterol-lowering treatment program.

Niacin Extended-Release/Simvastatin Dosing

The dose of niacin extended-release/simvastatin that your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to the medication
  • Other medical conditions you may have
  • Other medications you may currently be taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Niacin Extended-Release/Simvastatin Dosage for more information.)
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Niacin Extended-Release/Simvastatin Information

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