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Side Effects of Niacin Extended-Release/Lovastatin

Common Niacin Extended-Release/Lovastatin Side Effects

Niacin extended-release/lovastatin has been studied in clinical trials, with hundreds of people having been evaluated. In these studies, side effects were documented and compared to side effects that occurred in a similar group of people taking either lovastatin or extended-release niacin alone (rather than the combination of the two).
Based on these studies, the most common side effects of niacin extended-release/lovastatin included:
  • Flushing (sudden reddening, warmth, and tingling, especially of the face, neck, and/or upper chest) -- in up to 71 percent of people
  • Infection -- up to 20 percent
  • Headaches -- up to 9 percent
  • Pain -- up to 8 percent
  • Nausea -- up to 7 percent
  • Itching -- up to 7 percent.
Other commonly reported side effects (occurring in 3 to 6 percent of people) included:


In clinical studies, up to 19 percent of people stopped taking niacin extended-release/lovastatin because of side effects. The main reason for stopping the medicine was flushing. Flushing can last for several hours after taking niacin extended-release/lovastatin, and can vary in severity from person to person. Flushing may be accompanied by other side effects, such as:
  • Dizziness
  • A fast or forcefully beating heart
  • Shortness of breath
  • Sweating
  • Burning sensations of the skin
  • Chills
  • Swelling. 


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Niacin Extended-Release and Lovastatin Information

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