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Naltrexone Side Effects

Common Side Effects

Naltrexone has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people receiving the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, naltrexone side effects that occurred in at least 10 percent of people included:
  • Nausea
  • Vomiting
  • Insomnia
  • Anxiety
  • Nervousness
  • Abdominal (stomach) pain and cramps
  • Low energy
  • Joint pain and muscle pain
  • Headache.
Other common reactions, occurring in 1 percent to 10 percent of people, included:
Rare side effects, occurring in less than 1 percent of people, included but were not limited to:
  • Sinus problems, such as:
    • Nasal congestion
    • Runny nose
    • Sneezing
    • Excess phlegm or mucus
  • Sore throat
  • Cough
  • Itching
  • Heavy breathing
  • Hoarseness
  • Nosebleeds
  • Blood clots
  • Swelling of the arms, hands, legs, ankles, or feet
  • Gassiness
  • Hemorrhoids
  • Shoulder, leg, or knee pain
  • Tremors
  • More frequent urination
  • Painful urination
  • Decrease in sex drive
  • Oily skin
  • Acne
  • Hair loss
  • Cold sores
  • Bad dreams
  • Blurry vision
  • Sensitivity to light
  • Burning or aching of the eyes
  • Clogged ears
  • Ringing of the ears
  • Earache
  • Increased appetite
  • Changes in weight
  • Yawning
  • Fever
  • Dry mouth
  • Hot flashes
  • Feelings of coldness in the feet.
Drink Less Alcohol

Naltrexone Medication Information

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