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Low-Dose Naltrexone

What Is Naltrexone Used for in Low Doses?

There is some thought in the scientific community that very low doses of naltrexone may reduce the pain and swelling associated with certain autoimmune and inflammatory diseases. Some scientists have also hypothesized that low-dose naltrexone may prevent certain cells from growing and multiplying, which could be important in the treatment of cancer.
It is important to note, however, that low-dose naltrexone has not been approved by the U.S. Food and Drug Administration (FDA) to treat any medical problem. Therefore, it would be considered an "off-label" use. While many drugs are used for off-label reasons, and many can be quite effective when used in this fashion, it is not entirely known at this point whether using naltrexone in low doses is a safe and effective off-label treatment for any condition.

What Conditions Has Low-Dose Naltrexone Been Studied to Treat?

Low-dose naltrexone has been studied for the treatment of many different conditions, including but not limited to:
However, studies to date have primarily been limited to animal studies, anecdotal case reports, or small human studies. At this time, there is simply not enough evidence from large, well-controlled human studies to support the clinical use of low-dose naltrexone.

Final Thoughts

At this time, low-dose naltrexone has not been adequately studied to say for certain that it is an effective treatment for any medical condition. If you search for this topic on the Internet, you will find many organizations promoting its use.
However, at this time, its use is not widely accepted by healthcare providers. Scientists are continuing to study the medication, and future trials may be able to shed more light on the safety and effectiveness of low-dose naltrexone.
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