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Naltrexone Injection Dosage

The standard dose of naltrexone injection is 380 mg -- this dosage is used regardless of age, weight, or other factors. The medication is injected into a gluteal muscle every four weeks. Each injection will be administered by a healthcare provider.

An Introduction to Your Dosage of Naltrexone Injection

There is only one standard dose of naltrexone injection (Vivitrol®), regardless of your age, weight, or the reason you are taking it. As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Recommended Naltrexone Injection Dosing Guidelines

The usual recommended dosage for treating alcohol or opioid dependence is 380 mg every 4 weeks.
The active ingredient in naltrexone injections is naltrexone. Naltrexone also comes in the form of a tablet (Revia®), which is taken by mouth. If you have been taking naltrexone tablets, talk to your healthcare provider about how long you should wait between taking your last naltrexone tablet dose and starting naltrexone injections.

General Information on Taking Naltrexone Injection

Some considerations to keep in mind during treatment with naltrexone injections include the following:
  • Naltrexone injections are given as an injection into a muscle (an intramuscular, or IM, injection). The injections are usually given once a month.
  • The injections must be administered by a healthcare provider, using a special needle that comes with the medication.
  • Naltrexone injections are given into the gluteal muscle (buttocks muscle). Your healthcare provider will alternate which buttock the injection is given into each month.
  • You should not receive naltrexone injections if you have taken an opioid or opioid-containing medication in the past 7 to 10 days.
  • You should carry a medical ID card or wear a medical bracelet stating you use naltrexone injections. This is important so you will receive appropriate care in the event of an emergency.
  • For the medication to work properly, it must be used as prescribed. Do not stop receiving your injections without your healthcare provider's approval.
  • If you are unsure about anything related to your dosage, please talk with your healthcare provider, nurse, or pharmacist.
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Naltrexone Injection Information

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