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Nasal Naloxone

If you have received high doses of opioid medications, your healthcare provider may prescribe naloxone hydrochloride (Narcan®) to reverse their effects. This prescription medication is approved for use in adults, children, and infants.
Naloxone is used to reverse respiratory depression and other potentially dangerous side effects that can result from receiving high amounts of opioids. It can also help increase blood pressure in people with septic shock.
There are also some occasions when healthcare providers prescribe this drug for "off-label" (unapproved) uses. For example, using naloxone as a nasal spray for treating an opioid overdose would be considered an off-label use. This drug may also be used off-label to treat itching or constipation caused by opioids.
(Click What Is Naloxone Used For? for a complete overview of using this drug to reverse the effects of opioid medications. This article also discusses naloxone works and whether it is safe for use in newborns.)
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