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Muromonab-CD3 Side Effects

Common Side Effects

Muromonab-CD3 has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people given muromonab-CD3 were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
 
In these studies, the most common side effects of muromonab-CD3 included but were not limited to:
 
  • Fever -- in up to 77 percent of people
  • Infections, including bacterial, viral, and fungal infections -- up to 47 percent
  • Chills -- up to 43 percent
  • Diarrhea -- up to 37 percent
  • Nausea -- up to 32 percent
  • Headaches -- up to 28 percent
  • Increased heart rate (tachycardia) -- up to 26 percent
  • Vomiting -- up to 25 percent
  • Low blood pressure (hypotension) -- up to 25 percent
  • High blood pressure (hypertension) -- up to 19 percent
  • Shortness of breath -- up to 16 percent
  • Tremors -- up to 14 percent
  • Rash -- up to 14 percent
  • Swelling of the arms, hands, legs, ankles, feet, or other body parts -- up to 12 percent.
 
Other common side effects, occurring in 1 percent to 10 percent of people, included but were not limited to:
 
  • Weakness or loss of strength
  • Fatigue
  • Chest pain (angina)
  • Itching
  • Decreased white blood cell counts
  • Abnormally fast or deep breathing (hyperventilation)
  • Joint and muscle pain
  • Abdominal (stomach) and intestinal pain (gastrointestinal pain)
  • Sweating
  • Redness of the skin
  • Tiredness and drowsiness
  • Dizziness
  • Confusion
  • Breathing problems, including wheezing
  • Nervousness
  • General discomfort
  • Decreased appetite
  • A slow or abnormal heartbeat
  • Depression
  • Kidney problems
  • Ringing in the ears
  • Eye sensitivity to the light
  • Pneumonia
  • Anemia (low red blood cell count)
  • Low platelet count
  • Seizures
  • Blockage of a blood vessel, such as from blood clots.
 

Muromonab-CD3 Medication Information

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