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Precautions and Warnings With Midazolam

There are many precautions and warnings with midazolam to be aware of before starting the medication. For example, to help ensure a safe treatment process, you should let your healthcare provider know if you have glaucoma, chronic obstructive pulmonary disease (COPD), or any allergies. There are also certain people who should not take midazolam, such as those who have acute narrow-angle glaucoma or those who are allergic to any of the ingredients in midazolam.

Midazolam: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking midazolam (Versed®) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Midazolam

Some of the warnings and precautions to be aware of prior to taking midazolam include the following:
  • Make sure your healthcare provider is equipped for and capable of handling breathing problems and other emergencies that midazolam may cause, especially if your procedure will not be performed in a hospital.
  • As with all benzodiazepines, midazolam is a controlled substance, which means that it has the potential to be abused. There are special rules and regulations for prescribing and dispensing midazolam.
  • People with chronic obstructive pulmonary disease (COPD) may be more sensitive to the negative affects of midazolam on breathing. If you have COPD, be sure to inform your healthcare provider and anesthesiologist.
  • Midazolam can cause difficulty breathing, which may be life threatening. This risk is increased when midazolam is combined with alcohol, narcotics, or other medications or substances that cause drowsiness and sedation (see Drug Interactions With Midazolam for more information).
  • The effects of midazolam may last quite a while after your surgery or procedure, even if you feel fine. In general, you should not drive yourself home or make any important decisions after your surgery or procedure.
  • Midazolam is considered a pregnancy Category D medication. This means that it is probably not safe for use during pregnancy. Talk to your healthcare provider about the risks and benefits of using the drug during pregnancy (see Versed and Pregnancy).
  • Midazolam passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Versed and Breastfeeding).
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