Drug Interactions With Midazolam

Among the medications that may potentially cause drug interactions with midazolam are seizure medications, antidepressants, and antipsychotic medications. Some of these drug interactions can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. To reduce your chances of developing midazolam interactions, be sure to talk with your pharmacist or healthcare provider about any interactions that may apply to you.

An Overview of Drug Interactions With Midazolam

Midazolam (Versed®) can potentially interact with other medications. Some of these medicines that may lead to midazolam interactions include:
 
o Clozapine (Clozaril®, FazaClo®)
  • Barbiturates, including:
o Amobarbital (Amytal®)
o Butalbital (Fioricet®, Fiorinal®)
o Pentobarbital (Nembutal®)
o Phenobarbital (Luminal®)
o Secobarbital (Seconal®) 
  • Certain antibiotics or antifungals, including:
o Erythromycin (Ery-Tab®)
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Telithromycin (Ketek®) 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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