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Drug Interactions With Midazolam

Cimetidine (Tagamet)
Cimetidine can increase the level of midazolam in your blood or may increase the time it takes for your body to remove midazolam from the blood. Make sure your healthcare provider or anesthesiologist is aware that you are taking cimetidine before using midazolam.
 
Diltiazem (Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Dilt-XR, Taztia XT, Tiazac)
Diltiazem can increase the level of midazolam in your blood or may increase the time it takes for your body to remove midazolam from the blood. Make sure your healthcare provider or anesthesiologist is aware that you are taking diltiazem before using midazolam.
 
Narcotics or Opiates
Combining an opiate or narcotic with midazolam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure your healthcare provider or anesthesiologist is aware that you are taking narcotics or opiates before using midazolam.
 
Other Benzodiazepines
Combining midazolam with other benzodiazepines can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure your healthcare provider or anesthesiologist is aware that you are taking another benzodiazepine before using midazolam.
 
Seizure Medications
Combining a seizure medication with midazolam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure your healthcare provider or anesthesiologist is aware that you are taking a seizure medication before using midazolam.
 
Sleep Medications
Combining a sleep medication with midazolam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure your healthcare provider or anesthesiologist is aware that you are taking a sleep medication before using midazolam.
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