Mevacor Drug Interactions

When medicines such as miconazole, verapamil, and niacin are taken with Mevacor, drug interactions may occur, resulting in complications or side effects. Because a combination of medications can cause your body to metabolize the drugs differently than intended, combining Mevacor and certain other drugs can increase your risk of developing serious side effects such as severe muscle problems.

  

Mevacor Drug Interactions: An Introduction

Mevacor® (lovastatin) may potentially interact with a number of other medications. Some of the medications that may lead to Mevacor interactions include:
 
  • Amiodarone (Cordarone®, Pacerone®)
  • Certain antibiotics, such as:
     
 
  • Certain antifungals, such as:
     
    • Fluconazole (Diflucan®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Posaconazole (Noxafil®)
    • Voriconazole (VFEND®)
 
 
 
Some of these drug interactions with Mevacor may increase your risk for developing serious muscle problems (see Mevacor and Muscle Pain). If you experience unexplained muscle pain, tenderness, or weakness, especially if you have a fever or you feel ill, it is important to contact your healthcare provider immediately.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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