Mevacor Drug Interactions
When medicines such as miconazole, verapamil, and niacin are taken with Mevacor, drug interactions may occur, resulting in complications or side effects. Because a combination of medications can cause your body to metabolize the drugs differently than intended, combining Mevacor and certain other drugs can increase your risk of developing serious side effects such as severe muscle problems.
Mevacor® (lovastatin) may potentially interact with a number of other medications. Some of the medications that may lead to Mevacor interactions include:
- Amiodarone (Cordarone®, Pacerone®)
- Certain antibiotics, such as:
- Certain antifungals, such as:
- Cobicistat-containing products (such as Stribild®)
- Colchicine (Colcrys®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Danazol (Danocrine®)
- Diltiazem (Cardizem®, Cardizem CD®, Cardizem LA®, Cartia XT®, Dilacor XR®, Dilt-CD®, Diltia XT®, Dilt-XR®, Taztia XT®, Tiazac®)
- Fibrates, such as:
- Grapefruit juice
- Nefazodone (Serzone®)
- Niacin (nicotinic acid, Niacor®, Nicolar®)
- Protease inhibitors, such as:
- Ranolazine (Ranexa®)
- Verapamil (Calan®, Calan SR, Verelan®, Verelan PM, Isoptin®, Covera-HS®)
- Warfarin (Coumadin®, Jantoven®).
Some of these drug interactions with Mevacor may increase your risk for developing serious muscle problems (see Mevacor and Muscle Pain). If you experience unexplained muscle pain, tenderness, or weakness, especially if you have a fever or you feel ill, it is important to contact your healthcare provider immediately.