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Mevacor Drug Interactions

More Detail About Mevacor Interactions

The following sections explain in detail the potentially negative interactions that can occur when Mevacor is combined with any of the drugs listed above.
 
Amiodarone
Taking both amiodarone and Mevacor increases the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your Mevacor dosage should not exceed 40 mg per day.
 
Certain Antibiotics
Some antibiotics may increase the level of Mevacor in your blood, increasing the risk of Mevacor side effects, including dangerous side effects such as myopathy or rhabdomyolysis. These medications should not be taken together with Mevacor; instead alternative antibiotics should be recommended. If no suitable alternatives are available, you should stop taking Mevacor while taking the antibiotic.
 
Certain Antifungals
Some antifungal medications may increase the level of Mevacor in your blood, increasing the risk of Mevacor side effects, including dangerous side effects such as myopathy or rhabdomyolysis. These medications should not be taken together with Mevacor; instead alternative antifungal should be recommended. If no suitable alternatives are available, you should stop taking Mevacor while taking the antifungal.
 
Cobicistat
The risk of serious side effects (including myopathy or rhabdomyolysis) is increased when combining Mevacor with cobicistat-containing medications, such as Stribild. In general, these medications should not be taken together.
 
Colchicine
There have been a few cases of serious muscle problems, such as myopathy or rhabdomyolysis, in people taking Mevacor with colchicine. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments.
  
Cyclosporine
Taking both cyclosporine and Mevacor together may increase the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. These medications should not be taken together.
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Mevacor Medication

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