Mevacor and Muscle Pain

Mevacor Medication

Drug Interactions With Mevacor and Muscle Pain

Serious muscle problems are more common when Mevacor is first started or when the dosage is increased, but they can happen at any time. Certain medicines can increase the risk for serious muscle problems when taken with Mevacor. These medicines include:

Amiodarone (Cordarone^®, Pacerone^®)
Antifungals, such as:
- Fluconazole (Diflucan^®)
- Itraconazole (Sporanox^®)
- Ketoconazole (Nizoral^®)
- Miconazole
- Posaconazole (Noxafil^®)
- Voriconazole (VFEND^®)

Certain antibiotics, such as:
- Erythromycin
- Clarithromycin (Biaxin^®)
- Telithromycin (Ketek^®)

Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Danazol (Danocrine^®)
Fibrates, such as:
- Fenofibrate (Antara™, Lofibra™, Tricor^®, Triglide™)
- Gemfibrozil (Lopid^®)

Niacin (nicotinic acid, Niacor^®, Nicolar^®)
Protease inhibitors, such as:
- Amprenavir (Agenerase^®)
- Atazanavir (Reyataz^®)
- Darunavir (Prezista™)
- Fosamprenavir (Lexiva^®)
- Indinavir (Crixivan^®)
- Lopinavir and ritonavir (Kaletra^®)
- Nelfinavir (Viracept^®)
- Ritonavir (Norvir^®)
- Saquinavir (Invirase^®)
- Tipranavir (Aptivus^®)

Nefazodone (Serzone^®)
Verapamil (Calan^®, Calan SR, Verelan^®, Verelan PM, Isoptin^®, Covera-HS^®).

Grapefruit juice, grapefruit products, and grapefruit supplements should also be avoided (see Grapefruit Juice and Mevacor).

(Mevacor and Muscle Pain Continued: Page 3)
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