Mevacor and Muscle Aches: Drug Interactions
Serious muscle problems are more common when
Mevacor is first started or when the dosage is increased, but they can happen at any time. There are also certain medicines that, when taken with Mevacor, can increase the risk for serious muscle problems. These medicines include:
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Danazol (Danocrine®)
- Fibrates (Lopid®, Tricor®, Antara®, Lipofen®, Triglide®, Lofibra™)
- Niacin (nicotinic acid, Niacor®, Nicolar®)
- Erythromycin
- Clarithromycin
- Telithromycin
- HIV protease inhibitors
- Nefazodone (Serzone®)
- Amiodarone (Cordarone®)
- Verapamil (Calan®, Calan SR, Verelan®, Verelan PM, Isoptin®, Covera-HS®)
- Antifungals, such as ketoconazole (Nizoral®), fluconazole (Diflucan®) and itraconazole (Sporanox®).
Grapefruit juice and grapefruit products (including grapefruit supplements) should also be avoided.
Mevacor and Muscle Aches: Summary
For people taking Mevacor, muscle aches and pain can be a problem, especially when first starting the medication or when the dosage is increased. Talk to your healthcare provider if muscle aches become a problem while you are taking Mevacor. Your healthcare provider will be able to give you other suggestions for dealing with muscle aches. If the muscle aches continue, your healthcare provider may recommend adjusting the
Mevacor dosage or switching to another
cholesterol medication.
Also, if muscle aches, weakness, pain, or tenderness occurs (especially if you also have a fever or feel sick), it can mean there is a serious problem. Call your healthcare provider immediately.