Precautions and Warnings With Meperidine

There are many precautions and warnings with meperidine to be aware of, including knowing who should not use this drug. Although meperidine was once very popular, it is now recommended that it be avoided if possible (as serious side effects have resulted). Since meperidine has significant abuse potential, it is not a good choice for people with a history of alcohol or drug abuse.

Meperidine Hydrochloride Medication Information

What Should I Tell My Healthcare Provider Before Taking Meperidine?

You should talk with your healthcare provider prior to taking meperidine hydrochloride (Demerol^®) if you have:

A history of drug or alcohol dependence
Liver disease, such as cirrhosis, liver failure, or hepatitis
Kidney disease, such as kidney failure (renal failure)
An irregular heart rhythm, such as atrial fibrillation or atrial flutter
Seizures or epilepsy
Low blood pressure (hypotension)
Gallbladder or pancreas disease
Lung disease of any sort
A head injury or high intracranial pressure
Severe abdominal (stomach) pain
An underactive thyroid (hypothyroidism)
Asthma
Addison's disease
An enlarged prostate (benign prostatic hypertrophy, or BPH)
Seizures or epilepsy
Sickle cell anemia
Any allergies, including allergies to foods, dyes, or preservatives.

Also, let your healthcare provider know if you are:

Pregnant or thinking of becoming pregnant
Breastfeeding.

Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

(Precautions and Warnings With Meperidine Continued: Page 2)