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Drug Interactions With Medroxyprogesterone Subcutaneous Injection

When certain drugs are combined with medroxyprogesterone subcutaneous injection, negative interactions may occur. For example, if someone uses antibiotics and is also using medroxyprogesterone subcutaneous injections to prevent pregnancy, it might make the contraceptive less effective. To avoid this and other problems, make sure your healthcare provider knows about any other medication you are taking.

An Overview of Medroxyprogesterone Subcutaneous Injection Interactions

Medroxyprogesterone subcutaneous injection (depo-subQ Provera 104®) may potentially react with a number of other medications. Some of the drugs that can lead to interactions with medroxyprogesterone subcutaneous injection include but are not limited to:
  • Antibiotics
  • Certain anti-seizure medications, such as:
  • Corticosteroids, such as:
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
  • Griseofulvin (Grifulvin V®)
  • Protease inhibitors, such as:
  • Retinoids, such as:
  • Tranexamic acid (Cyklokapron®, Lysteda®).
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Medroxyprogesterone Subcutaneous Injection Information

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