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Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
  • An inability to tell if you are thirsty
  • An inability to make urine
  • Kidney disease, such as kidney failure
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Severe dehydration or malnutrition
  • Alcoholism or drink large amounts of alcohol
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Tolvaptan to learn more, including information on who should not take the drug.)

How Does It Work?

Tolvaptan works by blocking the effects of a hormone known as vasopressin. Vasopressin helps regulate the amount of water in the body. By blocking the effects of this hormone, tolvaptan causes more water to be removed as urine, without causing sodium to leave the body. This results in higher blood sodium levels. 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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