Drugs Home > Streptozocin Dosage

Your height and weight will be needed for your healthcare provider to calculate an appropriate streptozocin dosage. Other factors that may affect this amount include other medications you are taking and how you respond to streptozocin. This prescription chemotherapy drug comes as an injection that is either given rapidly or slowly over a period of up to six hours.

An Introduction to Your Dosage of Streptozocin

The dose of streptozocin (Zanosar®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • How you respond to and tolerate it
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Streptozocin Dosing Guidelines

Like many chemotherapy medicines, streptozocin dosing is based on body surface area, which is normally calculated using your height and weight. Doses based on body surface area are written as milligrams per meter squared (mg per m2).
Your healthcare provider may recommend one of two schedules for your treatment -- daily dosing or weekly dosing. The usual recommended daily dose of streptozocin is 500 mg per m2 once a day for five days in a row. This amount is normally repeated every six weeks until your cancer no longer responds to the medicine or you experience potentially serious side effects.
The usual recommended weekly dose of streptozocin is 1000 mg per m2 each week. Your healthcare provider may increase this amount if your cancer has not adequately responded after two weeks of treatment. The maximum recommended weekly dose of streptozocin is 1500 mg per m2. Weekly doses are normally repeated until the cancer no longer responds to the medicine or you experience potentially serious side effects.
People with kidney or liver disease may need lower streptozocin doses. People who experience potentially serious side effects may also need lower amounts.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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