Drugs Home > Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid

Sodium picosulfate/magnesium oxide/anhydrous citric acid is used before a colonoscopy to help clean out the colon. It comes as a powder that is mixed with water and taken prior to the procedure. This prescription medicine may not be suitable for people with certain allergies or medical conditions. Side effects include nausea, headaches, and vomiting.

What Is Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid?

Sodium picosulfate/magnesium oxide/anhydrous citric acid (Prepopik®) is a prescription medication licensed to cleanse the bowels before a colonoscopy in adults. This bowel cleansing is often called colonoscopy preparation or bowel prep. Of all the prescription bowel-prep products, this has the lowest volume of active ingredient you must drink (only two 5-ounce doses).
 
(Click What Is Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, sodium picosulfate/magnesium oxide/anhydrous citric acid can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects seen with sodium picosulfate/magnesium oxide/anhydrous citric acid may include but are not limited to:
 
 
(Click Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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