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People who have experienced organ rejection for several years without relief may benefit from Sandimmune. This drug is given along with a steroid to help prevent rejection. It comes in a few different forms and strengths, and is generally taken once a day. Side effects can include overgrowth of gum tissue and tremor, among other things.

What Is Sandimmune?

Sandimmune® (cyclosporine) is a prescription "immunosuppressant" medication approved to prevent transplant rejection after a kidney, liver, or heart transplant, in combination with a corticosteroid medication. It is also approved to treat chronic rejection (transplant rejection that occurs over years) in people who were already treated with another immunosuppressant.
Sandimmune contains cyclosporine, a medication that is also available in a modified, or slightly altered, form as Gengraf® or Neoral®. The modified form of cyclosporine is absorbed differently by the body, and is therefore not interchangeable with Sandimmune, which is unmodified.
(Click Sandimmune Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Sandimmune capsules are made by Catalent Pharma Solutions, LLC or R.P. Scherer GmbH. Sandimmune oral solution is made by Novartis Pharma S.A.S. The injection is made by Novartis Pharma Stein AG. All three products are distributed by Novartis Pharmaceuticals Corporation.

How Does Sandimmune Work?

Transplant rejection occurs when the body's immune system sees a transplanted organ as foreign and attacks it. Sandimmune works by suppressing the immune system. Because the immune system is less active when this medication is taken, transplant rejection is less likely to occur.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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