If you have uncomplicated (mild) malaria, a healthcare provider may prescribe Qualaquin. This medication comes in the form of a capsule and is taken every eight hours for seven days. It works by killing a specific parasite that is responsible for causing this blood infection. Some of the possible side effects include dizziness, headaches, and sweating.
What Is Qualaquin?
Qualaquin® (quinine sulfate) is a prescription medication licensed to treat uncomplicated (or mild) malaria.
This medication is made by Mutual Pharmaceutical Company, Inc., for AR Scientific, Inc.
How Does Qualaquin Work?
Qualaquin belongs to a class of drugs called antimalarials. Malaria is a blood infection caused by tiny parasites called Plasmodium. Qualaquin treats malaria by killing the Plasmodium parasites.
Although it is not entirely known how Qualaquin works, it is thought that the medication prevents Plasmodium from using blood glucose for energy and from making proteins and nucleic acid, which are essential for the parasite to live.
Clinical Effects of Qualaquin
The main active ingredient in Qualaquin is quinine. Clinical studies have shown that quinine can cure malaria when given alone or in combination with clindamycin or tetracycline.
In these studies, 80 to 100 percent of people with uncomplicated (mild) malaria were free from infection after receiving quinine for seven days. They remained infection-free for the entire study period (28 days).
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Qualaquin [package insert]. Philadelphia, PA: AR Scientific, Inc.;2010 June.
Micromedex Healthcare Series [Internet database]. Greenwood Village, CO: Thomson Reuters (Healthcare), Inc. Updated periodically. Accessed August 30, 2010.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 21, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed September 1, 2010.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed September 1, 2010.
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