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Pomalidomide is taken once a day to treat multiple myeloma. This prescription drug is reserved for use in people whose cancer has progressed after at least two other cancer drugs have been tried. Side effects are common and include shortness of breath, tiredness, and nausea. If you smoke cigarettes or have problems with your liver, it may not be safe to take pomalidomide.

What Is Pomalidomide?

Pomalidomide (Pomalyst®) is a prescription medication approved for the treatment of multiple myeloma, a cancer of the plasma cells. It is specifically approved for use in people whose cancer has progressed despite treatment with at least two other multiple myeloma medications, including lenalidomide (Revlimid®) and bortezomib (Velcade®).
(Click What Is Pomalidomide Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, pomalidomide can cause side effects. And, like many other cancer treatments, the side effects can be significant. In fact, the majority of people who take pomalidomide will experience at least one side effect during treatment.
Common pomalidomide side effects include but are not limited to:
  • Tiredness and weakness
  • Low white blood cell counts
  • Low red blood cell counts
  • Shortness of breath
  • Constipation
  • Nausea.
(Click Pomalidomide Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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