Drugs Home > Precautions and Warnings With Polyethylene Glycol Electrolyte Solution

If you are about to take polyethylene glycol electrolyte solution before a gastrointestinal procedure, it is important to know that this laxative may not be safe for people with kidney disease, a bowel obstruction, or certain other medical problems. Other safety precautions with polyethylene glycol electrolyte solution include warnings of potentially serious problems that may occur, such as dehydration, seizures, or low blood sugar levels.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking polyethylene glycol electrolyte solution (colyte®, GoLYTELY®, MoviPrep®, NuLYTELY®, TriLyte®) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Ever had a seizure
  • Difficulty swallowing or frequent vomiting
  • A hole in the bowel (bowel perforation)
  • Intestinal blockage (obstruction)
  • Nausea, vomiting, abdominal (stomach) pain, and abdominal swelling (distention), which may be signs of a bowel obstruction
  • An electrolyte imbalance (such as low blood sodium or potassium)
  • Been on a low-salt diet
  • Gastric retention (a condition in which there is a delayed emptying of stomach contents into the intestines)
  • Inflammatory bowel disease, or other bowel problems, such as ulcerative colitis, toxic colitis, toxic megacolon, and ileus
  • A genetic condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • Ever had hemolytic anemia
  • Phenylketonuria
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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