Drugs Home > Phenergan Warnings and Precautions

Before starting Phenergan, warnings and precautions for the medication should be reviewed with your healthcare provider. It is important to know that the drug can cause potentially fatal slow or irregular breathing, increase the risk of seizures, and cause a life-threatening condition called neuroleptic malignant syndrome. You should never give Phenergan to a child under two years old, as the drug can cause fatal breathing problems.

What Should I Tell My Healthcare Provider Before Taking Phenergan?

You should talk with your healthcare provider prior to taking Phenergan® (promethazine hydrochloride) if you have:
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding
  • Undergoing chemotherapy or radiation treatments.
     
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
It should be noted that this article applies only to Phenergan products that contain only promethazine as the active ingredient. Some cough syrups (such as Phenergan with Codeine) contain other active ingredients as well.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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