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Peginesatide is used to treat anemia in people who are undergoing dialysis for chronic kidney disease. It comes as an injection that is administered intravenously (through an IV) or subcutaneously (just under the skin) every four weeks. This prescription medicine may not be suitable for people with certain allergies or medical conditions. Side effects include nausea, shortness of breath, and diarrhea.

In February 2013, peginesatide was pulled from the market (all of the product was recalled) to investigate reports of dangerous allergic reactions, including fatal anaphylactic reactions, which appear to be occurring more frequently than anticipated. This medication will not be available until further notice.

What Is Peginesatide?

Peginesatide (Omontys®) is a prescription medication approved to treat anemia caused by chronic kidney disease (CKD) in adults on dialysis. It is injected just once a month.
(Click What Is Peginesatide Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, peginesatide may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common peginesatide side effects include but are not limited to:
  • Diarrhea
  • Shortness of breath
  • Nausea
  • Problems with your dialysis access site.
(Click Peginesatide Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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