Drugs Home > Drug Interactions With Nitroglycerin Tablets

If certain medications are taken together with nitroglycerin tablets, there is a possibility for negative drug interactions. Some of these reactions can make the medications less effective or increase your risk for complications, such as low blood pressure or heart attacks. Alcohol, anticholinergic medications, and blood pressure medicines are among the substances that can react with the nitroglycerin tablet.

An Overview of Nitroglycerin Tablet Interactions

The nitroglycerin tablet (Nitrostat®) may react with a number of other medications. Some of the drugs that can lead to interactions with nitroglycerin tablets include but are not limited to:
  • Alcohol
  • Alteplase (Activase®)
  • Anticholinergic medications, such as:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
  • Phenothiazine medications, such as:
  • Phosphodiesterase type-5 (PDE5) inhibitors, such as:


Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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