Drugs Home > Nicotine Nasal Spray

Nicotine nasal spray is commonly used as part of a smoking-cessation program. It should be used along with behavioral change strategies and other support mechanisms for maximum effect. The medication works to minimize symptoms of nicotine withdrawal, such as cravings. Most people have no problems with it -- the most commonly reported side effect was short-term nasal irritation.

What Is Nicotine Nasal Spray?

Nicotine nasal spray (Nicotrol® NS) is a prescription medication approved to help people quit smoking (known as smoking cessation) by reducing the uncomfortable symptoms of nicotine withdrawal that occur when people try to quit. It is sprayed into the nose. Nicotine nasal spray should be used as part of a complete smoking-cessation program that includes behavior change strategies, counseling, or support groups.
(Click What Is Nicotine Nasal Spray Used For? for more information on this topic, including possible off-label uses.)

Side Effects of Nicotine Nasal Spray

Just like any medicine, nicotine nasal spray can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Some of the common side effects seen with nicotine nasal spray include:
  • Nose or throat irritation
  • Runny nose
  • Watery eyes
  • Sneezing
  • Coughing.
(Click Nicotine Nasal Spray Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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