Drugs Home > Drug Interactions With Minoxidil
Combining certain medications with minoxidil may result in negative reactions. Even though minoxidil is applied topically to the scalp, sometimes enough of the medication can reach the bloodstream to interfere with other drugs. Interactions with minoxidil may occur with blood pressure medications, prostacyclin analogs, and certain topical products, to name a few.
An Overview of Minoxidil InteractionsMinoxidil (Rogaine®) is an over-the-counter (OTC) medication used to treat male and female pattern baldness. It may potentially interact with several other medications.
- Amifostine (Ethyol®)
- Blood pressure medications
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Diazoxide (Proglycem®)
- Guanethidine (Ismelin®)
- Phosphodiesterase type 5 inhibitors (PDE5 inhibitors), such as:
- Prostacyclin analogs, such as:
- Epoprostenol (Flolan®, Veletri®)
- Iloprost (Ventavis®)
- Treprostinil (Remodulin®, Tyvaso®)
- Corticosteroid creams and ointments, such as hydrocortisone (Cortaid®, Cortizone®, and several other products) or triamcinolone (Triderm® and several other products)
- Petrolatum or petroleum jelly (Vaseline®)
- Retinoid creams or gels, such as bexarotene (Targretin®) and tretinoin (Atralin™, Avita®, Renova®, Retin-A®, Tretin-X™).