Drugs Home > Mecasermin

If your child has growth problems, he or she may benefit from mecasermin. This prescription medicine is specifically designed for use in children and adolescents who do not make enough insulin-like growth factor (IGF-1), a hormone needed for human growth. It comes as a liquid that is injected twice daily just beneath the skin. Headaches, dizziness, and vomiting are possible side effects of the drug.


What Is Mecasermin?

Mecasermin (Increlex®) is a prescription medication approved to treat children who are very short for their age because their body does not make enough insulin-like growth factor-1 (IGF-1), a hormone that is important for human growth. This is known as severe primary IGF-1 deficiency.
It is also approved to treat children with growth hormone (GH) gene deletion, in cases when the child has developed antibodies against growth hormone treatment.
(Click What Is Mecasermin Used For? for more information, including possible off-label uses.)

Are There Side Effects?

As with any medicine, mecasermin can cause side effects. However, not everyone who uses the drug will experience side effects. Most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Some of the common mecasermin side effects include:
  • Low blood sugar (hypoglycemia)
  • Reactions at the injection site, such as bruising
  • Headache
  • Dizziness
  • Vomiting.
(Click Mecasermin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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