Drugs Home > Side Effects of Loteprednol

Some of the most common loteprednol side effects include eye discharge, itching, and redness. In most cases, reactions to these eye medications are usually minor and do not require medical attention. However, there are some potentially serious problems that should be reported to a healthcare provider right away, such as eye infections or difficulty breathing.

An Introduction to Loteprednol Side Effects

As with any medicine, loteprednol etabonate (Alrex®, Lotemax®) can cause side effects. However, not everyone who uses the medication will have problems. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with loteprednol. Your healthcare provider can discuss a more complete list with you.)

Serious Side Effects of Loteprednol

Some side effects with this medicine, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Glaucoma and high pressure within the eye, which can cause permanent damage
  • Eye infections (as steroids can suppress the immune system)
  • Perforation of the eye (in people who have a thinning of the eye surface due to certain diseases)
  • Signs of an allergic reaction to the medication, such as:
    • An unexplained rash or hives
    • Itching (more than the usual itching related to eye allergies)
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing or difficulty breathing.
Of course, any eye medication can cause problems (such as an eye infection) if it is contaminated, so make sure to avoid touching the tip of the dropper to any surface, including the surface of the eye. Report any signs of an eye infection (such as severe pain, swelling, or redness) to your healthcare provider right away.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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