Drugs Home > Drug Interactions With Leuprolide
Many diabetes drugs can potentially interact with leuprolide, including acarbose, insulin, metformin, and glimepiride. Leuprolide has been known to increase blood sugar, so if you already have diabetes, you may need to monitor your blood sugar more frequently during treatment. Before starting treatment with leuprolide, tell your healthcare provider about any other medications you are taking.
- Dipeptidyl peptidase-4 (DPP-4) inhibitors, such as:
- Glitazones and glitazone combination medications, such as:
- Metformin (Glucophage®, Glucophage XR®, Fortamet®, Glumetza®, Riomet®)
- Sulfonylureas or sulfonylurea combination medications, such as:
- Chlorpropamide (Diabinese®)
- Glimepiride (Amaryl®)
- Glimepiride and pioglitazone (Duetact®)
- Glimepiride and rosiglitazone (Avandaryl®)
- Glipizide (Glucotrol®, Glucotrol XL®)
- Glipizide and metformin (Metaglip®)
- Glyburide (DiaBeta®, Micronase®, Glynase®)
- Glyburide and metformin (Glucovance®)
- Tolazamide (Tolinase®)
- Tolbutamide (Orinase®).