Drugs Home > Lansoprazole Side Effects

Some of the most common side effects of lansoprazole include nausea, diarrhea, abdominal pain, and constipation. There are many other potential side effects associated with the drug; however, they tend to be rare, meaning they occur in less than 1 percent of people. These side effects include such things as gout, allergic reactions, weight gain, and high blood pressure.

An Introduction to Side Effects of Lansoprazole

There are a number of possible side effects associated with lansoprazole (marketed under the brand name Prevacid®). However, not everyone who takes lansoprazole will experience side effects. In fact, most people tolerate it well. When side effects do occur, in most cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
(The side effects discussed below are not a complete list of side effects reported with the medication. Your healthcare provider can discuss a more complete list of lansoprazole side effects with you.)

Common Lansoprazole Side Effects

Lansoprazole has been studied extensively in clinical trials, with over 10,000 people worldwide having been evaluated. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
Based on these studies, the most common side effects of lansoprazole were:
  • Abdominal pain (2.1 percent of people)
  • Constipation (1 percent of people)
  • Diarrhea (3.8 percent of people)
  • Nausea (1.3 percent of people).
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Last reviewed by: Kristi Monson, PharmD;
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