Drugs Home > Ivacaftor Side Effects

Clinical studies have shown that headaches, nasal congestion, and throat pain are some of the most commonly reported side effects of ivacaftor. Although many people tolerate this medication without reactions, serious problems could occur. Let your healthcare provider know right away if you develop reactions such as unexplained swelling, breathing problems, or yellowing of the whites of the eyes or skin.

An Introduction to Side Effects of Ivacaftor

Just like any medicine, ivacaftor (Kalydeco™) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with ivacaftor. Your healthcare provider can discuss a more complete list with you.)
 

Ivacaftor Side Effects to Report

Some side effects of ivacaftor are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling (especially of the lips, mouth, or throat)
    • Wheezing or other breathing problems
 
  • Signs of liver damage, such as:
 
    • Upper-right abdominal (stomach) pain
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Loss of appetite
    • Nausea and vomiting
    • Dark urine.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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