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Adults who have hereditary angioedema (HAE) may benefit from treatment with icatibant. This prescription drug is used to treat HAE attacks, which cause swelling beneath the skin. It is given as an injection just under the skin. Although most people tolerate the medication well, side effects are possible and may include fever, dizziness, and reactions at the injection site.

What Is Icatibant?

Icatibant (Firazyr®) is a prescription medication approved to treat acute attacks of hereditary angioedema (HAE), a rare genetic condition that causes sudden episodes of swelling beneath the skin. Icatibant belongs to a class of medicines known as bradykinin inhibitors.
(Click What Is Icatibant Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, icatibant can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common icatibant side effects include but are not limited to:
  • Reactions at the site of the injection, such as redness, burning, bruising, or irritation
  • Fever
  • Dizziness.
(Click Icatibant Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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