Drugs Home > Fluconazole

Fluconazole is approved for the treatment of certain fungal infections, including thrush and vaginal yeast infections. It is also licensed to prevent yeast infections in people undergoing bone marrow transplantations. The medication is available by prescription only and comes in tablet, liquid suspension, and injectable form. It works by inhibiting an enzyme that is used by fungal cells to make ergosterol.

What Is Fluconazole?

Fluconazole (Diflucan®) is a prescription antifungal medication. It is approved to treat a variety of different fungal infections, such as yeast infections and thrush. It can also be used to prevent yeast infections in people undergoing bone marrow transplantations.
(Click What Is Fluconazole Used For? for more information, including possible off-label uses.)

Potential Side Effects

Just like any medicine, fluconazole may cause side effects. However, not everyone who takes the drug will experience problems. Most people actually tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Some of the most common side effects include but are not limited to:
  • Headache
  • Nausea
  • Abdominal pain (stomach pain).
(Click Fluconazole Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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