Drugs Home > Fentanyl Buccal Soluble Film

Fentanyl buccal soluble film is a narcotic used for relieving cancer pain that breaks through around-the-clock pain medication. This prescription medication comes in the form of a small film that dissolves in the mouth on the inside of the cheek. This drug has a high risk for abuse and overdose, so make sure you know how to use it properly and store it securely.

What Is Fentanyl Buccal Soluble Film?

Fentanyl buccal soluble film (Onsolis™) is an opioid pain medication used to treat breakthrough pain (sudden bursts of pain that "break through" around-the-clock pain medication) in people with cancer who are regularly taking an opioid medication for their constant cancer pain. Fentanyl buccal soluble film comes as a small film, which is dissolved in the mouth inside of the cheek.
Fentanyl buccal soluble film is considered a Schedule II controlled substance because it has a high potential for abuse. Schedule II controlled substances have the highest abuse potential of all prescription medications. There are strict laws and regulations controlling their use.
(Click What Is Fentanyl Buccal Soluble Film Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, fentanyl buccal soluble film can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects seen with fentanyl buccal soluble film may include but are not limited to:
  • Nausea
  • Vomiting
  • Weakness
  • Dehydration
  • Tiredness
  • Shortness of breath.
(Click Side Effects of Fentanyl Buccal Soluble Film to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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