A healthcare provider may give a woman dinoprostone vaginal suppositories in several situations, such as to cause an abortion, to remove the contents of the uterus after a missed miscarriage, or to treat gestational trophoblastic disease. The suppository is inserted high in the vagina by a healthcare provider in a hospital setting. Vomiting, diarrhea, and fever are among the possible side effects.
What Is Dinoprostone Vaginal Suppository?
Dinoprostone vaginal suppository (Prostin E2®) is a prescription medication approved to cause an abortion or to remove any contents remaining in the womb (the uterus) after a "missed abortion" or "missed miscarriage" (when a fetus dies in the womb but is not naturally miscarried as normal). It is also approved to treat a cancer-like condition of the uterus known as gestational trophoblastic disease.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Prostin E2 [package insert]. New York, NY: Pharmacia and Upjohn Company;2006 May.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed January 27, 2012.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed January 23, 2012.
Dinoprostone. Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012. Available from Wolters Kluwer Health, Inc. Accessed January 25, 2012.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click