Drugs Home > Precautions and Warnings With Dextromethorphan and Quinidine
You may not be able to safely take dextromethorphan and quinidine if you have certain medical conditions, such as high blood pressure, heart problems, or Alzheimer's disease. Other precautions and warnings with dextromethorphan and quinidine involve the danger of potentially serious drug interactions, the risk of developing heart rhythm problems, and the safety of using it when pregnant or breastfeeding.
What Should I Tell My Healthcare Provider Before Taking Dextromethorphan and Quinidine?You should talk with your healthcare provider prior to taking dextromethorphan and quinidine (Nuedexta™) if you have:
- Heart failure or coronary artery disease
- A history of an abnormal electrocardiogram (ECG)
- Heart rhythm problems, including QT prolongation or atrioventricular (AV) block
- A family history of heart problems
- High blood pressure, not controlled on medication
- A history of a stroke
- Myasthenia gravis, a condition that affects the muscles and nerves
- Alzheimer's disease
- Difficulty urinating (urinary retention)
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Any allergies, including to foods, dyes, or preservatives.
- Pregnant or thinking of becoming pregnant