Drugs Home > Dextromethorphan and Quinidine

Clinical Effects of Dextromethorphan and Quinidine

In clinical studies, people who took dextromethorphan and quinidine for 12 weeks had fewer involuntary episodes of crying and laughing during the study period than people who took a placebo (a "sugar pill" that does not contain any active ingredients). Some people noticed an improvement within as little as a week. Half of all the people taking dextromethorphan and quinidine did not experience any episodes during the last two weeks of the study.

When and How to Take This Medication

Some general considerations to keep in mind during treatment with dextromethorphan and quinidine include the following:
  • This medication comes in capsule form. It is usually taken by mouth once or twice a day.
  • Dextromethorphan and quinidine can be taken with or without food. Try taking it with food if it seems to bother your stomach.
  • Try to take your doses at the same time each day to keep an even level of the medication in your bloodstream.
  • Your healthcare provider may periodically try to take you off this medication. This is because pseudobulbar affect sometimes improves on its own, and you may no longer need the medication.
  • For the medication to work properly, it must be taken as prescribed.

Storage Information

Dextromethorphan and quinidine should be stored at room temperature, away from moisture and heat. Keep this and all other medications out of the reach of children.

Is There a Generic Version?

This medication is not available in generic form (see Generic Nuedexta for more information).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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